Balanced adrenal glands are a key part of being Bulletproof. Your adrenals create and regulate cortisol, which makes them essential for hacking stress. When your adrenals work the way they should, you become more resilient, and you have a much easier time taking on life’s challenges.

But if you’re overwhelmed by chronic stress, your adrenals can get burnt out from constantly producing cortisol. The result is adrenal fatigue. Your natural cortisol rhythm becomes irregular — sometimes you produce too much cortisol, sometimes not enough — and you can struggle to make other hormones, like androstenedione (the precursor to testosterone).

Considering Spironolactone for Acne? Spironolactone (Aldactone) is one of the most common treatments for hormonal acne, as well as alopecia (hair loss), oily skin, and hirsutism. It is effective at lowering testosterone levels by inhibiting synthesis of this hormone, increasing sex hormone binding globulin and blocking androgen receptors. It may also reduce an enzyme known as 5-alpha reductase, which is responsible for converting testosterone into a potent androgen called Dihydrotestosterone or DHT.